PDT IN CHINA
Photodynamic therapy (PDT) originated in Germany. In 1900, Oscar Raab, a medical student at the University of Munich in Germany, accidentally discovered that paramecium grew well in a dark environment in a culture medium containing acridine and some similar dye solutions, but died when exposed to light; Further research has found that this phenomenon is not only related to the concentration of acridine dyes, but also to the intensity of light in the experiment. This is the first experimental study on photodynamic therapy, confirming that light combined with chemicals can induce cell death, opening the prelude to photodynamic research.
